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Countries that favor development and innovation have recognized the healing benefits of CBD oil https://biocbdolja.se. The most recent legislation of medicinal and recreational marijuana legalization was in Canada in October 2018. Several small, limited studies have suggested that the oil may help stop cancer growth. In the meantime, CBD oil is already being used to manage cancer symptoms and the side effects of cancer treatments.

A Cure For Cancer?

Researchers and scientists have not found a definitive answer, but they have been some promising evidence over the last few decades. For instance, a 1975 study reported that CBD oil slowed the growth of lung cancer in mice. A 2014 study also found that THC and CBD may help prime cancer cells respond better to radiation therapy. However, this study was performed in cells, not in animals or humans.

CBD Oil and Apoptosis

Apoptosis is defined as the natural process in the body where the cells are destroyed as part of a particular organism’s growth. Cancer cells grow as an abnormal process in the body since they no longer acknowledge the body’s signals that encourage or destroy cell growth. With the growth and division of these cells, they become more uncontrollable. And because they don’t respond to apoptosis, they tend to accelerate cell proliferation while ignoring the other signals from normal cells. This explains why the endocannabinoid system remains an extremely important system in the body since it also helps in regulating cell growth and death. Cancer cells reproduce faster than the endocannabinoid system can handle, while invading through the normal tissues and spreading throughout the body in a process called metastasis. The are two primary receptors in the endocannabinoid system. One is the CB1 receptors (found mostly in the brain) and the other one is the CB2 receptors (primarily found in the immune system). THC is an active compound in cannabis which binds to the CB1 receptors and is responsible for mood, behavior, and other cerebral functions. CBD on the other hand, latches onto the CB2 receptors and tells these receptors if there are invaders which are detrimental to the body. The apoptotic process by the receptors could be achieved through the de novo synthesis of ceramide and sphingolipid which encourages cell destruction. From the moment they bind together, the receptor activation can then help the endocannabinoid system in signaling an antitumorigenic warning. This means, it impairs cancer development through inhibiting reproduction, metastasis, and tumor angiogenesis.

As a treatment for cancer

Solid evidence exists to support the idea that cannabinoids can reduce tumor growth in animal models of cancer. CBD may also enhance uptake or increase potency of certain drugs used in the treatment of cancer.
  • A 2019 review of in vitro and in vivo studies focusing on pancreatic cancer discovered that cannabinoids can help in slowing tumor growth, reduce tumor invasion, and induce tumor cell death. In the study, researchers wrote that studies into the effectiveness of different formulations, dosing, and precise mode of action are lacking and urgently needed.
  • A 2019 study gave indication that CBD could provoke cell death and make glioblastoma cells more sensitive to radiation, but with no effect on healthy cells.
  • A large, long-term study of men within the California Men’s Health Study cohort revealed that using cannabis may be inversely associated with bladder cancer risk. Nevertheless, a cause and effect relationship has not been established.
  • A 2014 study in experimental models of colon cancer in vivo suggests that CBD may inhibit the spread of colorectal cancer cells.
  • A review of 35 in vitro and in vivo studies found that cannabinoids are promising compounds in the treatment of gliomas.
  • Other studies revealed the efficacy of CBD in pre-clinical models of metastatic breast cancer. The research found that CBD significantly decreased breast cancer cell proliferation and invasion.
These are just a few studies that addresses the potential of CBD oil in the treatment of cancer. Having said that, it is too early to say that CBD is a safe and effective treatment for cancer in humans. CBD should not be considered a substitute for other cancer treatment.

Conclusion

Although further studies are yet to be reviewed to prove these claims, the cannabinoids in cannabis oil have undoubtedly helped cancer patients one way or another. Chemotherapy patients have been using cannabis oil to alleviate their post-chemo side effects like nausea, vomiting, fatigue, inflammation, neuropathic pain, immune suppression, and loss of appetite. Currently, based on research and studies, the evidence is not enough to say whether cannabis oil has the potential to cure cancer or not. Larger, long-term studies in humans are needed to determine whether it works and, if it does, how to use it safely and effectively.

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